Fat-binding polymers

阅读量:

20

申请(专利)号:

US20020307151

申请日期:

2002-11-27

公开/公告号:

US2003175236A1

公开/公告日期:

2003-09-18

申请(专利权)人:

MANDEVILLE W. HARRY;WHITESIDES GEORGE M.;HOLMES-FARLEY STEPHEN RANDALL

发明人:

WH MandevilleGM WhitesidesSR Holmes-Farley

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被引量:

54

摘要:

The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. The methods comprise the step of orally administering to a mammal, such as a human, a therapeutically effective amount of one or more fat-binding polymers. The administration of the fat-binding polymer of the invention facilitates the removal of fat from the body prior to digestion, with minimal side effects and low toxicity. In a preferred embodiment, the one or more fat-binding polymers are administered in combination with one or more lipase inibitors, for example, lipstatin and tetrahydrolipstatin.

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2006
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