MicroRNA-Cancer Connection: The Beginning of a New Tale
摘要：
Cancer initiation and progression can involve microRNAs (miRNA), which are small noncoding RNAs that can regulate gene expression. Their expression profiles can be used for the classification, diagnosis, and prognosis of human malignancies. Loss or amplification of miRNA genes has been reported in a variety of cancers, and altered patterns of miRNA expression may affect cell cycle and survival programs. Germ-line and somatic mutations in miRNAs or polymorphisms in the mRNAs targeted by miRNAs may also contribute to cancer predisposition and progression. We propose that alterations in miRNA genes play a critical role in the pathophysiology of many, perhaps all, human cancers.
展开
关键词：
Animals Humans Neoplasms Genetic Predisposition to Disease MicroRNAs Nucleotide Mapping Mutation
DOI：
10.1158/0008-5472.CAN-06-0800
被引量：
年份：
2006
Taylor & Francis
掌桥科研
万方医学
Semantic Scholar
(全网免费下载)
doi.org
查看更多
NCBI
Europe PMC
Oxford Univ Press
AACR
(全网免费下载)
AACR
(全网免费下载)
AACR
ResearchGate
(全网免费下载)
ResearchGate
Citeseer
Citeseer
(全网免费下载)
EBSCO
theoncologist.alphamedpress.org
mendeley.com
bloodjournal.org
onAcademic
jeccr.com
199.171.202.195
fasebj.org
erc.endocrinology-journals.org
reproduction-online.org
ar.iiarjournals.org
cbio.mines-paristech.fr
(全网免费下载)
bioscirep.org
molecular-cancer.com
genesdev.cshlp.org
SAGE
clinchem.org
biolreprod.org
jacionline.org
jasn.asnjournals.org
jleukbio.org
gastrojournal.org
scienceopen.com
core.ac.uk
readcube.com
mdanderson.influuent.utsystem.edu
pubfacts.com
Semantic Scholar
(全网免费下载)
AACR
(全网免费下载)
AACR
(全网免费下载)
ResearchGate
(全网免费下载)
Citeseer
(全网免费下载)
cbio.mines-paristech.fr
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
