Synthesis of Indomethacin Conjugates with D-Glucosamine
摘要:
Two series of indomethacin conjugates with D-glucosamine were prepared with the objectives of reducing ulcerogenic potency, increasing the bioavailability of indomethacin and exerting the coordinative effects on osteoarthritis. The structures of the conjugates were identified by ^1H NMR and ^13C NMR. The ester conjugates inhibited edema as potent as indomethacin.
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DOI:
CNKI:SUN:FXKB.0.2005-02-009
被引量:
年份:
2005
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