ESCHERICHIA COLI MUTANTS AND METHODS OF USE THEREOF
申请(专利)号：
US20070312739
申请日期：
2007-11-20
公开/公告号：
US2010092511A1
公开/公告日期：
2010-04-15
申请(专利权)人：
MATTHEW K. WALDOR;THERESA D. HO
被引量：
摘要：
The present invention provides methods and compositions for production of gram-negative bacterial mutants that are defective in intestinal colonization capacity and sensitive to infection by bacteriophage P1. Thus the present invention provides immunogenic compositions for the prevention or attenuation of food- and water-borne illnesses associated with ingestion of bacteria such as enterohemorrhagic
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