Hot Water-Promoted Ring-Opening of Epoxides and Aziridines by Water and Other Nucleopliles

来自 EBSCO

阅读量:

39

作者:

Z WangYT CuiZB XuJ Qu

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摘要:

Effective hydrolysis of epoxides and aziridines was conducted by heating them in water at 60 or 100 °C. Other types of nucleophile such as amines, sodium azide, and thiophenol could also efficiently open epoxides and aziridines in hot water. It was proposed that hot water acted as a modest acid catalyst, reactant, and solvent in the hydrolysis reactions.

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DOI:

10.1021/jo702401t

被引量:

61

年份:

2008

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2011
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