INHIBITION OF HISTONE ACETYLTRANSFERASES BY CTK7A AND METHODS THEREOF
申请(专利)号：
EP20100813423
申请日期：
2010-09-06
公开/公告号：
EP2475769A1
公开/公告日期：
2012-07-18
申请(专利权)人：
JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH
被引量：
摘要：
The present disclosure relates to a method for inhibiting histone acetyltransferases by derivative of curcumin, particularly CTK7A. The present disclosure also relates to identification of induction of autoacetylation of p300 and its inhibition by CTK7A. The disclosure also relates to induction of NPM1 and GAPDH overexpression and corresponding hyperacetylation of histone and methods thereof.
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