Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage
摘要:
The synthesis of several novel coumarin derivatives with a 7-azomethine linkage was carried out starting from 7-formyl-coumarin. The compounds were tested in vivo for their anti-inflammatory activity and in vitro for their antioxidant ability. Compounds 3a and 3e possess significant protection against carrageenin induced rat paw edema.
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DOI:
10.1016/j.bmcl.2003.11.060
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年份:
2004
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