The Structure of Human Argonaute-2 in Complex with miR-20a

阅读量:

102

作者:

E ElkayamCD KuhnA TociljA HaaseE GreeneG HannonL Joshua-Tor

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摘要:

The crystal structure of human Argonaute-2, the "slicer" in RNA interference, loaded with a miRNA with roles in development and cancer provides a framework to understand the functions of this essential enzyme.

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DOI:

10.1016/j.cell.2012.05.017

被引量:

481

年份:

2012

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