GAMMA-HYDROXYBUTYRIC ACID FOR TREATMENT OF ALCOHOL WITHDRAWAL SYNDROME
摘要:
The effect of gamma-hydroxybutyric acid (GHB) on ethanol withdrawal syndrome in alcoholics was investigated in a randomised double-blind study. Patients with withdrawal symptoms were treated either with GHB (orally in a syrup preparation) (11 patients) or with the syrup alone (12). GHB treatment (50 mg/kg) led to a prompt reduction in withdrawal symptoms, such as tremors, sweating, nausea, depression, anxiety, and restlessness. The only side-effect was dizziness. GHB may be useful in the management of alcohol withdrawal syndrome in man.
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DOI:
10.1016/S0140-6736(89)90842-8
被引量:
年份:
1989
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