Primary extranodal and nodal non-Hodgkin's lymphomaA survey of a population-based registry

阅读量：

作者：

R Otter，WBJ Gerrits，MMVD Sandt，J Hermans，R Willemze

展开

摘要：

In a population-based registry, there were 580 patients with non-Hodgkin's lymphoma (NHL); 236 had primary extranodal lymphoma ( 41%). The initial localization of the primary extranodal lymphomas varied markedly, although 36% were primary gastrointestinal lymphomas. Histological classification was performed by a regional panel of pathologists according to the Kiel Classification and the International Working Formulation. Twelve per cent of the patients with nodal NHL had a localized disease in contrast to 40% with primary extranodal NHL. Low grade lymphomas were encountered in 30 and 10% of the patients with primary nodal and extranodal NHL, respectively. Recurrence-free survival rate for patients with localized low-grade malignancy and disseminated intermediate grade NHL is significantly better for extranodal lymphoma than for nodal NHL. Patients with disseminated high-grade extranodal NHL had the worst prognosis of all. We conclude that primary nodal and primary extranodal lymphomas should be considered as distinctive and separate entities.

展开

关键词：

OVARIAN CANCER RADIOTHERAPY SURVIVAL

DOI：

10.1016/0277-5379(89)90416-1

被引量：

327

年份：

1989