Oral transmucosal ketamine: an effective premedication in children
摘要：
The oral cavity offers a simple, painless way of drug administration. For this reason, we used oral transmucosal ketamine (5–6 mg·kg 1 ) for premedication in 15 children and compared it with intranasal ketamine (5–6 mg·kg 1 ), placebo and intramuscular ketamine (5–6 mg·kg 1 ). Oral transmucosal ketamine (OTK) provided effective sedation, facilitated i.v. line insertion and was accepted with pleasure by the patients (as lollipops). The lollipops produced a slight increase in gastric volumes but did not affect gastric pH. In conclusion OTK has been shown to be an effective, harmless preoperative medication in paediatric patients.
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DOI：
10.1046/j.1460-9592.1996.d01-9.x
被引量：
年份：
1996
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