ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder.
摘要：
Variability in antidepressant response is due to genetic and environmental factors. Among genetic factors, the ones controlling for availability of the drug at the target site are interesting candidates. Multidrug resistance 1 = 0.011). Furthermore, the wild variants haplotype (3435C–2677G–1236T) resulted associated with poor response ( = 0.006).To our best knowledge, this study is the first suggestion of a possible association of ABCB1 variants with SSRIs response.
展开
关键词：
HAM-D Hamilton Rating Scale for Depression ABCB1 Multidrug resistance 1 P-gp P-glycoprotein SCID-I The Structured Clinical Interview for DSM-IV Axis I Disorders SNPs single nucleotide polymorphisms
DOI：
10.1016/j.pnpbp.2007.09.003
被引量：
年份：
2008
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
