Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B-cell lymphoma.

来自掌桥科研

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阅读量：

171

作者：

PG Isaacson，J Spencer

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摘要：

Lymphomas of the gastrointestinal tract, salivary glands, lung and thyroid are grouped together as tumours arising in mucosa-associated lymphoid tissue. The great majority of them are of B-cell origin but distinctive T-cell lymphomas are also recognized in the gastrointestinal tract. These lymphomas tend to remain localized for prolonged periods but, whereas the B-cell group respond favourably to local therapy, the T-cell group are associated with severe morbidity and their overall prognosis is extremely poor. Accepted histological classifications of non-Hodgkin's lymphomas are difficult to apply to these tumours. In this paper their morphological features are reviewed; recent findings based on immunohistochemistry and DNA analysis are presented; and the biological behaviour of these tumours is discussed insofar as they offer insight into mucosal immunological mechanisms.

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关键词：

mucosal lymphoma centrocyte-like cells marginal zone cells gastric lymphoma salivary gland lymphoma

DOI：

10.1111/j.1365-2559.1987.tb02654.x

被引量：

5206

年份：

1987