Building oligonucleotide therapeutics using non-natural chemistries - ScienceDirect
摘要：
-methyl sense strand and a phosphorothioate antisense strand. The first fully modified aptamer (2′--methyl) was reported in 2005. It is expected that future candidate therapeutic oligonucleotides will have even more drug-like characteristics as a result of the inclusion of modified nucleotides.
展开
关键词：
PEPTIDE NUCLEIC-ACIDS IN-VITRO SELECTION ANTISENSE OLIGONUCLEOTIDE COMBINATORIAL SELECTION DYSTROPHIN EXPRESSION MACULAR DEGENERATION MAMMALIAN-CELLS DOUBLE-BLIND KAPPA-B RNA
DOI：
10.1016/j.cbpa.2006.10.001
被引量：
年份：
2006
相似文献
参考文献
引证文献
来源期刊
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
