Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta

阅读量:

35

申请(专利)号:

13/163597

申请日期:

06/17/2011

公开/公告号:

US20120015964

公开/公告日期:

Jun 26, 2012

发明人:

KW FowlerD HuangEA KesickiHC OoiA OliverF RuanJ TreibergKD Puri

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被引量:

120

摘要:

Compounds that inhibit P13Kδ activity, including compounds that selectively inhibit P13Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (P13Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which P13Kδ plays a role in leukocyte function, using the compounds also are disclosed.

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