Fabrication of plastic microfluid channels by imprinting methods.

来自掌桥科研

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阅读量：

197

作者：

L Martynova，LE Locascio，Michacl Gaitan

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摘要：

Microfluidic devices have been fabricated on poly(methyl methacrylate) substrates by two independent imprinting techniques. First-generation devices were fabricated using a small-diameter wire to create an impression in plastics softened by low-temperature heating. The resulting devices are limited to only simple linear channel designs but are readily produced at low cost. Second-generation devices with more complex microchannel arrangements were fabricated by imprinting the plastic substrates using an inverse three-dimensional image of the device micromachined on a silicon wafer. This micromachined template may be used repeatedly to generate devices reproducibly. Fluorescent analtyes were used to demonstrate reproducible electrophoretic injections. An immunoassay was also performed in an imprinted device as a demonstration of future applications.

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关键词：

Polymethyl Methacrylate Indicators and Reagents Semiconductors Silicon

DOI：

10.1021/ac970558y

被引量：

1008

年份：

1997