Induced Hyperthermia in the Treatment of Cancer
摘要：
The term "hyperthermia" summarizes the treatment of malignant diseases by application of heat by using different techniques. Hyperthermia is usually applied as an adjunct to an established treatment modality claiming intratumoral temperatures in the range of 40–43°C. Several clinical phase-III trials have demonstrated improvements in clinical outcome when locoregional hyperthermia is added to radio- and/or chemotherapy in patients with locally advanced or recurrent superficial and pelvic tumors. Further studies revealed a benefit for hyperthermic chemoperfusion as adjuvant therapy in patients with abdominal malignancies or malignant melanoma of the extremities. Finally, the addition of whole-body hyperthermia to systemic chemotherapy has revealed promising results in a number of recent phase – II studies. This chapter gives a summary on the recent results in clinical hyperthermia research, and points out the most interesting future developments.
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关键词：
Hyperthermia Induced therapy Combined modality review Academic Breast neoplasms Colorectal neoplasms Head and neck neoplasms Lymphatic metastases
DOI：
10.1007/978-90-481-9704-0_21
被引量：
年份：
2011
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