Rafts defined: a report on the Keystone symposium on lipid rafts and cell function

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126

作者:

LJ Pike

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摘要:

The recent Keystone Symposium on Lipid Rafts and Cell Function (March 23-28, 2006 in Steamboat Springs, CO) brought together biophysicists, biochemists, and cell biologists to discuss the structure and function of lipid rafts. What emerged from the meeting was a consensus definition of a membrane raft: "Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions." This definition helps to clarify current thinking in a field that has been plagued by the heterogeneous and sometimes ephemeral nature of its subject.

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关键词:

Membrane Microdomains

DOI:

10.1194/jlr.E600002-JLR200

被引量:

1890

年份:

2006

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2009
被引量:240

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