摘要：

Trimethylsilyl trifluoromethanesulphonate in trifluoroacetic and has been found to cleave, in the presence of thioanisole, a number of protecting groups currently employed in peptide synthesis, without significant side reactions and with a much faster rate of reaction than trifluoromethanesulphonic acid in trifluoroacetic acid; this new deprotecting reagent has geen used in solution and solid phase peptide syntheses of nueromedin U-25 (a 25-residue peptide) and a rabit stomach peptide (an 8-residue peptide), respectively.

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