摘要：

Four new briaranes, nui-inoalides A-D, (6-9) are described. They were isolated from octocorals collected in Pohnpei and Ant atoll, Micronesia. The absolute stereochemistry of the known briarane juncin E (5) was determined. Nui-inoalide A (6) and the known gemmacolides A, B, and D (2-4) exhibit immunomodulatory activity.

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