Method to identify analyte-binding ligands

阅读量:

13

申请(专利)号:

PCT/US1990/006333

申请日期:

19901031

公开/公告号:

WO1991006356A1

申请(专利权)人:

发明人:

KAUVAR, Lawrence, M.

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国省代号:

WO

被引量:

111

摘要:

The invention provides methods to obtain panels of low molecular weight polymers resulting from varying constituent monomers, which panels are systematically diverse with respect to two or more variables. The panels can be screened for members (paralogs) which are capable of specifically binding a target moiety. Such paralogs are useful for chromatographic separations and purifications of desired analytes and in binding assays, such as immunoassays, involving said analytes, as well as for any purpose which requires said specific binding. The invention also provides kits for these determinations, and methods to synthesize panels of candidate paralogs and use of these panels to generate analyte profiles and cross reactivity matrices.

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2001
被引量:10

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