Apoptosis and Clearance of Apoptotic Cells
摘要：
Some forms of regulated cell death, such as apoptosis, are precipitated by the activation of cysteine proteases of the caspase family, including caspase 8, 9, and 3. Other caspases, such as caspase 1 and 4, are well known for their pro-inflammatory functions but regulate cell death in a limited number of pathophysiological settings. Accumulating evidence suggests that the most conserved...
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关键词：
apoptosis efferocytosis macrophages phosphatidylserine flippase scramblase caspase TIM4 TAM receptors
DOI：
10.1146/annurev-immunol-042617-053010
被引量：
年份：
2018
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