Selected patented cross-coupling reaction technologies.
摘要：
A number of significant products commercialized or in the developmental phase, possess aromatic carbon-carbon and the aromatic carbon-nitrogen bonds which can be assembled by organometallic catalyst cross-coupling reactions. Thus, the scale-up of any new and general technology for the formation of these bonds can be of great industrial significance. An overview is given of palladium-, nickel-, copper-, and iron-catalyzed coupling reactions that provide many valuable and versatile pathways for discovery chemistry as well as large-scale synthesis and manufacture. It is shown that many important classes of pharmaceuticals would be difficult to prepare without reactions such as the Heck, Negishi, and Sonogashira reactions.
展开
关键词：
organic chemistry, review pharmacology, medicinal chemistry, vaccines, serums C‐C bond formation
DOI：
10.1002/chin.200641254
被引量：
年份：
2006
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
