Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells
摘要：
Interleukin 13 (IL-13) is a recently described protein secreted by activated T cells which is a potent in vitro modulator of human monocyte and B-cell functions. The data, reviewed here by Gerard Zurawski and Jan de Vries, shows that IL-13 shares biological activities with IL-4, their genes are closely linked in both the human and mouse genomes, and there is sequence homology between IL-13 and IL-4 proteins. Although the cloned IL-4 receptor protein (IL-4R) does not bind IL-13, it appears that the functional IL-4R and IL-13R share a common subunit that is important for signal transduction.
展开
关键词：
Animals Humans Mice Leukocytes, Mononuclear Interleukins Interleukin-4 Interleukin-13 Sequence Homology, Amino Acid Amino Acid Sequence Molecular Sequence Data
DOI：
10.1016/0167-5699(94)90021-3
被引量：
年份：
1994
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
