Importance ofSaccharomyces cerevisiaeOxidosqualene-Lanosterol Cyclase Tyrosine 707 Residue for Chair-Boat Bicyclic Ring Formation and Deprotonation Reactions

阅读量:

34

作者:

Tung-KungWuTsai-TingWangCheng-HsiangChangYuan-TingLiuWen-ShiangShie

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摘要:

An efficient synthesis of alpha,beta-unsaturated esters by treatment of the corresponding acids with alkyl or aryl carbonochloridate, triethylamine, and acetonitrile was accomplished for the first time under microwave irradiation for 10 min. The esters 1b-24b were isolated in 71-97% yield.

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DOI:

10.1021/ol802036c

被引量:

32

年份:

2008

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来源期刊

Organic Letters
2008年11月06日

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2012
被引量:9

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