Measurement of changes in vital capacity as a means of detecting pulmonary reactions to inhaled aerosolized allergenic extracts in asthmatic subjects
摘要：
1. 1. It was shown that a reduction in vital capacity followed the inhalation of aerosolized extracts of certain pollens and dust in ten asthmatic subjects. 2. 2. Tests could be carried out with little discomfort to the subject, although mild asthmatic manifestations usually occurred. 3. 3. In some instances a fall in vital capacity was observed in the absence of signs or subjective symptoms of asthma. 4. 4. Our limited experience indicates that this method may be helpful in diagnosis. The technique has the advantage that pulmonary reactions inditinguishable from spontaneous asthma may be produced and measured under controlled conditions. 5. 5. The possible value of this method in studying the effect of drugs on the asthmalike response is pointed out.
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DOI：
10.1016/0021-8707(48)90096-3
被引量：
年份：
1948
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