摘要：

Dithioesters IV a-d obtained by Michael-type addition of N-aryldithiocarbamic acids IIIa,b to 3-aryl-5-benzylidenerhodanines IIa,b undergo intramolecular chemoselective heterocyclizations with concentrated H2SO4, NaOH, and CH3I to afford 3,7-diaryl-5-(arylimino)-2,3,5,7-tetrahydrothiazolo[4,5-d][1,3]dithiin-2-thiones Va-d, 3,4,7-triaryl-2,3,4,5,7-pentahydrothiazolo[4,5-d][1,3]thiazine-2,5-dithiones VIa-d, and 3,7-diaryl-5-(arylimino)-2,3,5,7-tetrahydrothiazolo[5,4-e][1,3]oxathiin-2-thiones VIIa-d, respectively. Fungitoxicities of the dithioesters and their cyclized products were evaluated in vitro against Aspergillus niger and Fusarium oxysporium. Some of the compounds displayed activities comparable with that of the commercial fungicide Dithane M-45. Structure-activity relationships for the screened compounds are discussed.

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