DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS.
摘要:
Because of its low redox potential (-0.33 volts at pH 7), dithiothreitol (and its isomer, dithioerythritol) is capable of maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. Since this compound is a highly water-soluble solid with little odor and little tendency to be oxidized directly by air, it should prove much superior to the thiols now used as protective reagents for sulfhydryl groups.
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关键词:
Sulfides Alcohols Sulfhydryl Compounds Coenzyme A Chromatography Ultraviolet Rays Oxidation-Reduction Research
DOI:
10.1021/bi00892a002
被引量:
年份:
1964


























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