ELECTRON MICROSCOPE OBSERVATIONS ON TINGIBLE BODY MACROPHAGES IN MOUSE SPLEEN
摘要：
It is generally accepted that the tingible bodies (Körper) of Flemming (7) found in lymphatic tissue germinal centers represent phagocytized nuclear debris of small lymphocytes (1, 2, 6, 7, 11, and others) or both lymphocyte and erythrocyte debris (15). Several ideas about the significance of tingible bodies assume that they are small lymphocytes. The "graveyard theory " emphasizes the phagocytosis of pyknotic small lymphocytes (6, 9, 11). This theory was extended by Hamilton (8), Trowell (17), and Sundberg (16) who postulated reutilization of small lymphocytes in lymphocytopoiesis. Andrew (1) stressed the role of degeneration and phagocytosis of small lymphocytes in germinal centers as indicating that these centers
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DOI：
10.1083/jcb.19.3.641
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年份：
1963
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