Update 1 of: Synthesis and functionalization of indoles through palladium-catalyzed reactions.
摘要：
A team of scientists has made an effort to provide a comprehensive and updated overview of the latest developments in the palladium-catalyzed approaches to the preparation of indole derivatives with the emphasis on the rationale behind each synthetic procedure and the dependence of the results on a proper selection of reaction conditions. Palladium-catalyzed reactions are strongly dependent on a number of factors, such as the nature of stabilizing ligands, bases, additives, the combination of them, solvents, and temperature. All of these factors combine to afford a toolbox of tunable reaction conditions that make palladium chemistry so and unpredictable, providing an opportunity for an uninterrupted discovery of new, exciting chemistry despite the vast amount of studies.
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DOI：
10.1021/cr100403z
被引量：
年份：
2011
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