A Polymeric Radiostabilizer for Absorbable Polyesters
摘要:
A new strategy was developed to prepare absorbable copolymers of acceptable absorption profile and radiostability. This entailed the preparation of a crystallizable segmented copolymer of poly(ethylene 1,4-phenylene-bis-oxyacetate) (PEPBO) and polyglycolide (PG) units with PG as the dominant component of the system. Incorporation of about 10 mole percent of the polymeric radiostabilizer (PEPBO) into the PG chain leads to high strength fibers and substantially improves the in vivo strength retention; the copolymer was shown to be absorbable.
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