Drug Rediscovery to Prevent O -Label Prescription Reduces Health Care Costs: the Case of Tioguanine in e Netherlands

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CJJ MulderDPV AsseldonkNKHD Boer

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proceedings of the rst iopurine Task Force meeting. Dig Liver Dis 2011;43;270-276.9. Herrlinger KR, Kreisel W, Schwab M, et al. 6- ioguanine - e cacy and safety in chronic active Crohn's disease. Aliment Pharamcol er 2003;17:503-508.10. Dubinsky MC, Vasiliauskas EA, Singh H, et al. 6- ioguanine can cause serious liver injury in in ammatory bowel disease patients. Gastroenterology 2003;125:298-303.11. Oancea I, Png CW, Das I, et al. A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut 2013;62:594-605.

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