Role of glycosylation of Notch in development
摘要：
The Notch pathway is one of the major signaling pathways required for proper development in metazoans. Notch activity is regulated at numerous levels, and increasing evidence reveals the importance of "protein glycosylation" (modification of Notch receptors with sugars) for its regulation. In this review we summarize the significance of the Notch pathway in development and the players responsible for its glycosylation, and then discuss the molecular mechanisms by which protein glycosylation may regulate Notch function.
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DOI：
10.1016/j.semcdb.2010.03.003
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年份：
2010
Elsevier
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Elsevier
万方
掌桥科研
万方医学
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