Outcomes and Durability of Hepatic Reduction after Combined Partial Hepatectomy and Cyst Fenestration for Massive Polycystic Liver Disease Discussion

Hemming，Alan，W.，... - 《Journal of the American College of Surgeons》

Outcomes and Durability of Hepatic Reduction after Combined Partial Hepatectomy and Cyst Fenestration for Massive Polycystic Liver Disease

Partial hepatectomy and cyst fenestration (PHCF) selectively provides clinical benefit in highly聽symptomatic patients with polycystic liver disease (PLD)....

FT Chebib，A Harmon，MV Irazabal Mira，... - 《J Am Coll Surg》

Clinical management of polycystic liver disease

In this Grand Round we present a typical case of a woman with polycystic liver disease (PLD). This case prompts questions which both patients and clinician...

RMM Van Aerts，dLLFM Van，JM Banales，... - 《Journal of Hepatology》

The effect of disease severity markers on quality of life in autosomal dominant polycystic kidney disease: a systematic review, meta-analysis and meta-regr...

Little is known about determinants of quality of life (QoL) in autosomal dominant polycystic kidney disease (ADPKD). Recent studies suggest that QoL in ADP...

MK Neijenhuis，W Kievit，RD Perrone，... - 《Bmc Nephrology》

Recent Advances in the Management of Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It is characterized by the dysregulated growth of kidney cysts, resulting in end-stage kidney failure. By identifying the genes involved i...

FT Chebib，VE Torres - 《Clinical Journal of the American Society of Nephrology》

Clinical management of polycystic liver diseaseq

Fig. 1. Molecular background of PLD. (A) Overview of genetic distribution of ADPKD and ADPLD. Each colour represents the percentage of patients with a spec...

RMMV Aerts，LFMVD Laarschot，JM Banales，...

Clinical management of polycystic liver disease

Clinical vignette

van Aerts, Rene M. M.van de Laarschot, Liyanne F. M.Banales, Jesus M.Drenth, Joost P. H. - 《Journal of Hepatology the Journal of the European Association for the Study of the Liver》

TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling

Hepatic cystogenesis in Polycystic Liver Disease (PLD) is associated with increased levels of cAMP in cholangiocytes lining liver cysts. TGR5, a G protein-...

TV Masyuk，AI Masyuk，PM Lorenzo，... - 《Hepatology》

Clinical management of polycystic liver disease

Hepatic cystogenesis in Polycystic Liver Disease (PLD) is associated with increased levels of cAMP in cholangiocytes lining liver cysts. TGR5, a G protein-...

van，Aerts，Rene，... - 《Journal of Hepatology the Journal of the European Association for the Study of the Liver》

Recent Advances in the Management of Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD), the most common monogenic cause of ESKD, is characterized by relentless development of kidney cysts, ...

FT Chebib，VE Torres - 《Clinical Journal of the American Society of Nephrology》