摘要：

The objective of this investigation was to identify the type and quantify the leachability of plasticizer constituents from dental soft polymer gel systems. The clinical implications are that some plasticizers are known to be potentially toxic and in addition, loss of plasticizer results in changes in physical properties of dental soft polymers. A total of 7 different constitutents were quantitatively identified in the 8 solutions analysed by GC and GC-MS. Specimens of gel material (plasticized polymer) were evaluated for loss of plasticizer while subjected to both static and cyclic tests (1 Hz, 5 min, ± 12 N) in H 2O at 37°C. With one exception, cycled specimens did not yield greater extraction of ester. The use of 1- 14C EtOH indicated complete diffusion of ethanol from the gel within 24 h. The data indicate that a typical denture soft lining would leach between 10–40 times the level of ester that would normally be obtained from food and the environment, but would leach about one-tenth of the most stringent ADI value.

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