2-Acyl-tetrahydroisoquinoline-3-carboxylic acids: lead compounds with triple actions, peroxisome proliferator-activated receptor α/γ agonist and protein-tyrosine phosphatase 1B inhibitory activities.
摘要：
The compound (I) is a bioavailable peroxisome proliferator-activated receptor / dual agonist with a ten-fold weaker protein-tyrosine phosphatase 1B (PTP-1B) inhibitory activity than that of the PTP-1B inhibitor ertiprotafib.
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DOI：
10.1002/chin.201201200
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年份：
2012
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来源期刊
Chemical & Pharmaceutical Bulletin
2011/12/13 0:00:00
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2012
被引量：3
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