Insulin as a potent, specific growth factor in a rat hepatoma cell line
摘要：
A line of rat hepatoma cells in culture which, in response to serum starvation, become arrested in the early G$_{1}$ phase of growth, can be stimulated by insulin alone to enter the cell cycle and traverse S phase. A half-maximum response is observed at 30 to 70 picomolar concentrations and the maximum response is essentially identical to that found with optimum serum concentrations.
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DOI：
10.1126/science.7008195
被引量：
年份：
1981
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