Tablet for pharmaceutical use able to release active substances at successive times
申请(专利)号:
US07/139635
申请日期:
19871230
公开/公告号:
US04865849A
公开/公告日期:
19890912
申请(专利权)人:
PHARMIDEA
被引量:
摘要:
A tablet for pharmaceutical use able to release active substances at successive times, comprising at least; a first layer containing a portion of the active substance with suitable excipients, a barrier layer of polymer material gellable and/or soluble in water and/or aqueous liquids, which is interposed between said first layer and a third layer containing the remaining portion of active substance with suitable excipients, said barrier layer and said third layer being housed in a casing consisting of polymer material impermeable and insoluble in water or soluble in an alkaline environment.That part of the active substance not inserted in the casing is immediately available for dissolving, whereas the part inserted in the casing is available only after dissolution or rupture of the barrier layer and/or after solubilization of the casing.
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