Ir-Catalyzed Borylation of CH Bonds in N-Containing Heterocycles: Regioselectivity in the Synthesis of Heteroaryl Boronate Esters
摘要：
(Chemical Equation Presented) Blocking the way: Substitution at the 2-position in pyridines and other N-heterocycles blocks N-coordination to an Ir center. This steric hindrance provides a substrate-design criterion that allows the Ir-catalyzed borylation of C-H bonds, which can be followed by Suzuki-Miyaura cross-coupling in a one-pot reaction (see scheme; B 2pin2 = bis(pinacolato-O,O′)diboron, dtbpy = 4,4′-tBu2-2,2′-bipyridine).
展开
DOI：
10.1002/anie.200503047
被引量：
年份：
2006
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
来源期刊
Angewandte Chemie International Edition
2006/01/09
引用走势
2008
被引量：54
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
