摘要：

This paper mainly describes the development, synthesis and applications of silicon-based Lewis acids R3SiX [X=I, OTf, NTf2, C(C6F5)Tf2, etc.] and (R3SiX+MLn). They were principally used to catalyze aldol, allylation, Diels-Alder, ene and Friedel-Crafts reactions. SLAs were used in 0.5～20 mol%, and the yields of the catalyzed reactions varied from moderate to excellent with the different reactivity of sili- con-based Lewis acids. The order of the reactivities is R3SiNTf2R3SiOTf, (R3SiX+MLn)R3SiX. The development and applications of chiral SLAs are also reviewed. When chiral trialkylsilyl bis(perfluoromethanesulfonyl)imides were used as catalysts for Diels-Alder reaction of cyclopentadiene and methyl acrylate, ee value of the reaction was up to 54%.

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