Intravenous Tissue Plasminogen Activator Ameliorates the Outcome of Hyperacute Embolic Stroke

We report the results of a double-blind, placebo-controlled, multicenter trial on the efficacy of intravenous recombinant tissue plasminogen activator (rt-...

T Yamaguchi，T Hayakawa，H Kiuchi - 《Cerebrovascular Diseases》

Changing physicians' practices.

Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicin...

PJ Greco，JM Eisenberg - 《New England Journal of Medicine》

Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke

An open angiography-based, dose rate escalation study on the effect of intravenous infusion of recombinant tissue plasminogen activator(rt-PA) on cerebral ...

 - 《Annals of Neurology》

Recovery of motor function after stroke.

The natural history of recovery of motor function after stroke is described using data from a 1-year community-based study in Auckland, New Zealand. Of 680...

R Bonita，R Beaglehole - Stroke; a journal of cerebral circulation

Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease.

In this retrospective analysis we report our treatment experience in 65 consecutive patients with clinical signs of severe brainstem ischemia with angiogra...

W Hacke，H Zeumer，A Ferbert，... - 《Stroke》

Low-molecular-weight heparin for the treatment of acute ischemic stroke.

BACKGROUND: Despite doubts about their efficacy and concern about their safety, antithrombotic agents are often used to treat acute ischemic stroke. Recent...

R Kay，KS Wong，YL Yu，... - 《N Engl J Med》

Iatrogenic illness on a general medical service at a university hospital.

We found that 36% of 815 consecutive patients on a general medical service of a university hospital had an iatrogenic illness. In 9% of all persons admitte...

K Steel，PM Gertman，C Crescenzi，... - 《N Engl J Med》

The Canalith Repositioning Procedure: For Treatment of Benign Paroxysmal Positional Vertigo

The Canalith Repositioning Procedure (CRP) is designed to treat benign paroxysmal positional vertigo (BPPV) through induced out-migration of free-moving pa...

JM Epley - 《Otolaryngol Head Neck Surg》

Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: a meta-analysis.

Endoscopic hemostatic therapy for upper gastrointestinal bleeding is gaining widespread acceptance despite often conflicting results of randomized controll...

DJ Cook，GH Guyatt，BJ Salena，... - 《Gastroenterology》

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator

Neuronal degeneration in the hippocampus, a region of the brain important for acquisition of memory in humans, occurs in various pathological conditions, i...

SE Tsirka，A Gualandris，DG Amaral，... - 《Nature》