Immunophenotypic Analysis of Non-Hodgkin's Lymphomas in Chinese. A Study of 75 Cases in Hong Kong

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摘要：

The markers of 75 cases of were studied on cryostat sections using a panel of monoclonal antibodies. Forty-nine cases (65.3%) were found to express a B-cell phenotype, 23 cases (30.7%) a T-cell phenotype, 1 case (1.3%) a histiocytic phenotype and 2 cases (2.7%) no demonstrable surface markers. accounted for only 10.7% of the cases. Most expressed IgM-lambda or IgM-IgD-lambda, but a few failed to express surface immunoglobulin. Among the 23 cases of , 22 were of peripheral T-cell type; most were of helper-cell () phenotype and a significant number expressed J5 () and I2 (HLA-DR). The present study shows that the percentage of in Chinese is higher than in Caucasians, but lower than in Japanese. However, when the age-adjusted incidence of is considered, the incidence rates of in Hong Kong Chinese and Japanese in areas non-endemic for are similar; the incidence in Americans is similar or slightly lower. The major difference between the races is that , particularly the follicular type, is much rarer in Asians than Americans.

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Keywords Malignant lymphoma non-Hodgkin's lymphoma immunohistochemistry monoclonal antibodies epidemiology

DOI：

10.3109/00313028609087562

被引量：

157

年份：

1986