Isolation and characterization of oligosaccharides obtained from heparin by the action of heparinase
摘要：
The oligosaccharides obtained in an 85% yield by the action of purified heparinase on heparin were isolated and characterized. They all contained an α,β-unsaturated uronic acid on the nonreducing end showing that enzymatic degradation proceeds by an elimination reaction. The data also indicate that more than 30% of the glucosamine units are disulfated, with the second sulfate most likely on the 6 position. At least 30% and probably more of the uronic acid units appear to be nonsulfated. In agreement with earlier data, both glycosidic linkages of heparin are 1 → 4.
展开
DOI：
10.1021/bi00754a013
被引量：
年份：
1972
相似文献
参考文献
引证文献
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
