Toll-like receptors.
摘要:
This has led to the identification of several important roles for Toll receptors in mammals. This unit discusses mammalian Toll receptors (TLR1-10) that have an essential role in the innate immune recognition of microorganisms. Also discussed are TLR-mediated signaling pathways and antibodies that are available to detect specific TLRs.
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关键词:
Animals Mammals Humans Mice Drosophila Infection Adaptor Proteins, Signal Transducing Transcription Factors Membrane Glycoproteins Drosophila Proteins
DOI:
10.1146/annurev.immunol.21.120601.141126
被引量:
年份:
2003



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