摘要：

To investigate the chemical compounds from the twigs of Euonymus alatus,nine compounds were isolated and identified as( +)-Δ2,11-enaminousnic acid( 1),11-keto-β-boswellic acid( 2),acetyl 11-keto-β-boswellic acid( 3),camaldulenic acid( 4),betulinic acid( 5),6β-hydroxy-stigmast-4-en-3-one( 6),5-hydroxy-6,7-dimethoxyflavone( 7),ethyl 2,4-dihydroxy-6-methylbenzoate( 8),4,4'-dimethoxy-1,1'-biphenyl( 9). Their structures were elucidated by extensive spectroscopic analysis. Among them,compound 1was a new natural product. Compounds 2-4 and 7-9 were obtained from the Euonymus genus for the first time. In vitro study showed that compounds 2 and 3 showed significant anti-tumor activities to BEL-7402 and HCT-8 at the concentration of 10 mg·L- 1. The inhibition rate of compound 2 was 61. 78% and 68. 29%,whereas the inhibition rate of compound 3 had reached to 70. 91% and84. 07%.

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