Used as anti-thrombosis agents or as surfactants or cosurfactants for phospholipids intended for the preperation or stabilization of fluorocarbon emulsions, specially for biomedical applications
公开/公告号:
US6160161 A
公开/公告日期:
Dec 12, 2000
被引量:
摘要:
Per(poly)fluorinated polyoxyethylated carbamates of general formula (I) in which R F represents a perfluorinated group containing between 1 and 18 carbon atoms, W represents an oxo group or nothing, n is an integer from 1 to 10, m is from values 2 to 6, 80 or not defined, R is an alkyl group, R F W(CH 2 ) n+1 NHC(O)-- in which R F and W are as defined above, --(CHCH 3 CH 2 O) 30 (CH 2 CH 2 ) 80 C(O)NH(CH 2 ) n+1 R F in which R F is a perfluorinated group containing from 1 to 18 carbon atoms, R' is a hydrogen atom, an alkyl group containing between 1 and 18 carbon atoms which is optionally substituted, an optionally substituted aryl or aralkyl group, an allyl, methallyl or propargyl group or a perfluorinated chain having between 1 and 18 carbon atoms. These compounds can be used as anti-thrombosis agents or as surfactants or cosurfactants for phospholipids intended for the preparation or stabilization of fluorocarbon emulsions, notably emulsions for biomedical applications.
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