摘要：

Isolated, mammalian, adult bone marrow-derived, lineage negative hematopoietic stem cell populations (Lin HSCs) containing endothelial progenitor cells (EPCs) have been transfected with therapeutically useful genes. The transfected isolated stem cell populations of the invention are useful for delivering genes to the eye for cell-based gene therapy. Methods of preparing transfected isolated stem cell populations of the invention, and methods of treating ocular diseases and injury are also described.

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