Threshold ligand-receptor assay

This invention is directed to a ligand-receptor assay for determining the presence or amount of at least one target ligand, capable of competing with a ligand analogue conjugate for binding sites available on a ligand receptor, said liga...

Buechler Kenneth Francis，GE Valkirs，Anderson Richard Ray - EP

Rapid stick test for detection of ciguatoxin and other polyether toxins from tissues

A rapid stick test for the detection of ciguatoxin and other polyether toxins from fish tissue is disclosed. This is a relatively simple and rapid field test utilizing enzyme immunoassay technology for the detection of lipid toxin which ...

Y Hokama - US

Essai immunologique sur une surface solide prébloquée

A method for immunoassay of a viral antigen is performed on a membrane precoated with an inert protein. Nonimmunological capture of antigen takes place by ...

GL Henderson，RA Hoke，AC Hopkins，... - EP

Assay devices comprising a porous capture membrane in fluid- withdrawing contact with a nonabsorbent capillary network

Devices for use in heterogeneous ligand-receptor assays, having a porous member in contact with a nonabsorbent textured surface, where the surface texturing is such that a capillary network is formed when in fluid communication with the ...

MR Nowakowski，KF Buechler，RR Anderson，... - US

Biological magnetic colloids

Colloidal-sized paramagnetic particles are formed with affinity ligands directly adsorbed to their surface. The colloidal-sized particles can form a colloidal disperse phase which is distributed through an aqueous dispersion medium to fo...

CH Poynton，CL Reading - US

Solid support having antibodies immobilized thereon

Colloidal-sized paramagnetic particles are formed with affinity ligands directly adsorbed to their surface. The colloidal-sized particles can form a colloidal disperse phase which is distributed through an aqueous dispersion medium to fo...

 - WO

NON-COMPETITIVE THRESHOLD LIGAND-RECEPTOR ASSAYS

Assay methods for performing non-competitive ligand-receptor assays, where said assays provide a sensible result when the target ligand identified by the assay is present at a concentration greater than a defined threshold concentration....

BUECHLER Kenneth F.，VALKIRS Gunars E.，ANDERSON Richard R. - WO

Immunoassay on a preblocked solid surface

A method for immunoassay of a viral antigen is performed on a membrane precoated with an inert protein. Nonimmunological capture of antigen takes place by absorption onto the coated membrane. Captured antigen binds to a tracer which incl...

GL Henderson，RA Hoke，AC Hopkins，... - EP

Medical Kit and method for the determination of a drug

There is provided a novel medical kit which overcomes the problem with non-specific binding and interaction, thus providing a highly reliable method for qualitative or quantitative determination of a drug in a biological fluid. Said medi...

B Adnan，S Mohammed，J Ahmed - EP

Threshold ligand-receptor assay

This invention is directed to a ligand-receptor assay for determining the presence of at least one target ligand, capable of competing with a ligand analogue conjugate for binding sites available on a ligand receptor, said ligand analogu...

Buechler, Kenneth F，Valkirs, Gunars E，Anderson, Richard R