Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.
摘要:
Presents research which showed that caspase 3 cleaves the inhibitor of caspase-activated deoxyribonuclease (ICAD) and inactivates its CAD-inhibitory effect. Morphological characterization of apoptosis; What caspases are; DNA in apoptosis; Two caspase-3 cleavage sites in ICAD; Transformation of human Jurkat cells; ICAD transformants; Role of activation of CAD downstream of the caspase cascade.
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1998
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被引量:224
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