摘要：

The significance of imidazole heterocyclic nucleus in new drug development is worth mentioning. The wide range of its applica- tion has drawn an immense attention to the researchers to synthesize various imidazole derivatives, which may possess various pharmacological efficacies. In view of these observations we tried to track down the immense potentiality of imidazole ring system when accompanied with different scaffolds are reported herein. This study may help the researchers to hold the impor- tance of various substituent's in attenuating the pharmacological activity and incorporate these understanding in designing novel derivatives. KEY WORDS: Imidazole, Anti-inflammatory, anti-tubercular, Debus Synthesis

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